Orbital inflammatory disease secondary to a single-dose administration of zoledronic acid for treatment of postmenopausal osteoporosis

Scientific Area

Procianoy F, Procianoy E. Orbital inflammatory disease secondary to a single-dose administration of zoledronic acid for treatment of postmenopausal osteoporosis. Osteoporos Int. 2010;21(6):1057-1058. doi:10.1007/s00198-009-1048-1

Bisphosphonates have been related to ocular inflammation for a long time, mostly uveitis. In 2010 we treated this case of orbital inflammation that presented few days after an infusion of zoledronate. At that time, there were only 5 reported cases of orbital inflammation related to bisphosphonates (Pamidronate and Zoledronate). After this publication, dozens of similar cases have been reported, leading to the question: is bisphosphonate-induced orbital inflammation more common than once thought?

Dr. Fernando Procianoy

CRM-RS 26375

Commented Oculoplastic Papers

An objective tool to measure the effect of botulinum toxin in blepharospasm and hemifacial spasm

Commented by:
Midori Hentona Osaki

Scientific Area

Procianoy F, Procianoy E. Orbital inflammatory disease secondary to a single-dose administration of zoledronic acid for treatment of postmenopausal osteoporosis. Osteoporos Int. 2010;21(6):1057-1058. doi:10.1007/s00198-009-1048-1

Dr. Fernando Procianoy

Commented Oculoplastic Papers

An objective tool to measure the effect of botulinum toxin in blepharospasm and hemifacial spasm

Orbicularis oculi morphological alterations in affected and non-affected sides in hemifacial spasm

Immunohistochemical investigations of orbital infantile hemangiomas and adult encapsulated cavernous venous lesions (malformation versus hemangioma)

Analysis of blink activity and anomalous eyelid movements in patients with hemifacial spasm

Clinical and Radiological Evaluation of Periocular Infantile Hemangioma Treated With Oral Propranolol: A Case Series

Short-Incision Midface-Lift in Lower Blepharoplasty

Frontalis-Orbicularis Muscle Advancement for correction of upper eyelid ptosis: a systematic literature review

Frontalis Linkage Without Intraoperative Eyelid Elevation for the Management of Myopathic Ptosis

A Comparative Study of Clinical vs. Digital Exophthalmometry Measurement Methods

Orbital inflammatory disease secondary to a single-dose administration of zoledronic acid for treatment of postmenopausal osteoporosis

Characterization of Normal Mediolateral Angular Direction of Lower Eyelid Eyelashes in Different Age Groups

Effect of Low-Concentration, Nonmydriatic Selective Alpha-Adrenergic Agonist Eyedrops on Upper Eyelid Position

Intra and interobserver reliability of a modified distraction test based on digital images to assess lower eyelid horizontal tension

Effects of Muller’s muscle-conjunctival resection for ptosis on ocular surface scores and dry eye symptoms

Topical mitomycin in endoscopic-assisted probing for the treatment of congenital nasolacrimal duct obstruction in older children

Congenital Soft Tissue Deformities - Smith’s and Nesi Ophthalmic Plastic and Reconstructive Surgery text-book

Influence of involuntary eyelid spasms on corneal topographic and eyelid morphometric changes in patients with hemifacial spasm

Management of progressive myopathic blepharoptosis with daily application of octyl-2-cyanoacrylate liquid bandage

Infrabrow Skin Excision Associated with Upper Blepharoplasty to Address Significant Dermatochalasis with Lateral Hooding in Select Asian Patients